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卵巢癌是死亡率最高的女性生殖道恶性肿瘤患者对化疗药物易产生耐药是治疗失败的主要原因之一。研究卵巢癌耐药机理,探索可以指导临床用药的客观试验指标十分必要。核糖核苷酸还原酶亚单位(ribonucleotide reductase subunit M1,RRM1)是最近被广泛关注的一个肿瘤耐药基因,已证实其表
Ovarian cancer is one of the major causes of treatment failure in women with reproductive tract cancer who have the highest mortality and are resistant to chemotherapeutic drugs. To study the mechanism of drug resistance in ovarian cancer and to explore objective test indicators that can guide clinical drug use is very necessary. Ribonucleotide reductase subunit M1 (RRM1) is a tumor drug resistance gene that has been widely noticed recently, and it has been proved that