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目的 :分析1例A_3亚型患者输注交叉配血相合血液后出现抗-A_1的情况,探讨ABO血型亚型输血原则。方法:采用微柱凝胶法、试管法及吸收放散等检测方法确定1例A_3亚型患者,按照相容性输血原则,在交叉配血相合的情况下给予A型红细胞输注,6 d后再次输血时复查其血型。结果:患者定型为A3亚型并予输注A型红细胞,过程顺利,无不良反应,但于输血后第6天,患者产生抗-A_1。结论:对于ABO血型亚型患者,建议在非急救用血时选择供者红细胞抗原种类等于或少于患者自身的血液,避免刺激机体产生抗体,以便患者在紧急用血时可有更多选择。
OBJECTIVE: To analyze the anti-A 1 status after transfusion of blood cross-matched in 1 patient with type A_3 subtype to explore the principle of blood transfusion in ABO blood group. Methods: One case of type A_3 subtype was determined by microcolumn gel method, test tube method and absorption and dissipation test. A type of erythrocyte infusion was given in the case of cross matching with blood transfusion according to the principle of compatible blood transfusion. After 6 days Blood transfusion again review the blood type. Results: The patient was sub-type A3 and infused with type A erythrocytes. The course was smooth and no adverse reactions were observed. However, on the 6th day after transfusion, the patient developed anti-A_1. CONCLUSIONS: For patients with ABO subtypes, it is advisable to select donor erythrocyte antigen species equal to or less than the patient’s own blood for non-emergency rescue to avoid stimulating the body to produce antibodies so that patients may have more options for emergency use of blood.