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目的探讨急性出血坏死性胰腺炎所致胰性猝死者的临床和病理改变间的关系。方法尸检证实的急性胰腺出血坏死110例,对全身系统脏器作病理组织观察。结果无痛、昏迷、休克为主要表现,多器官损害为其特征,以肺水肿最突出占891%,心脏受累736%,脑水肿245%。脂餐、饮酒、胆石不是主要诱因,药物及多种应激因素应予重视。结论低容量休克、呼吸窘迫、急性心力衰竭、脑水肿是猝死的重要原因。有效抢救措施有待深入研究
Objective To investigate the relationship between the clinical and pathological changes in patients with sudden pancreatitis due to acute hemorrhagic necrotizing pancreatitis. Methods A total of 110 cases of acute pancreatic hemorrhage and necrosis confirmed by autopsy were observed in the pathological tissues of the systemic system. The results of painless, coma, shock as the main performance, multiple organ damage as its characteristics, the most prominent pulmonary edema accounted for 89.1%, heart involvement 73.6%, cerebral edema 24.5%. Fat meal, alcohol consumption, gallstone is not the main incentive, drugs and a variety of stress factors should be valued. Conclusions Low-capacity shock, respiratory distress, acute heart failure and cerebral edema are the major causes of sudden death. Effective rescue measures need further study