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癫癎发作可在二个方面改变血浆的激素水平:1,癫癎急性发作后几分钟内,血浆的高血糖素,肾上腺素、生长激素,崔乳激素、可的松以及胰岛素升高,其量和时间,是依据癫癎发作类型(例如:人的特发性全身性癫癎发作,抑郁症患者的电休克治疗,实验动物的药物诱发性癫癎发作)而不同。它们是癫癎发作时的不正常的主自性动作的直接结果,或是癫癎发作动作波及到脑,影响下丘脑释放固子的分泌量;或者是由于癫癎发作,产生系统变化的间接影响(例如:高糖血症可促进胰岛素分泌)。2、癫癎重复发作,可导致中枢神经递质功能改变。单胺系统内的变化,可通过释放
Epileptic seizures can alter plasma hormone levels in two ways: 1. Plasma levels of glucagon, epinephrine, growth hormone, tretinoin, cortisone, and insulin are elevated within minutes of the acute seizure The amount and timing vary depending on the type of epileptic seizure (eg, idiopathic generalized epileptic seizures in humans, electroshock treatment in depressed patients, and drug induced epileptic seizure in experimental animals). They are the direct result of an abnormal main self-action during epileptic seizures, or the onset of epileptic seizures affecting the brain, affecting the release of solid secretions from the hypothalamus, or indirect changes that cause systemic changes due to epileptic seizures Effects (eg hyperglycaemia promotes insulin secretion). Epilepsy recurrent seizures, can lead to changes in neurotransmitter function of the central nervous system. Changes within the monoamine system can be released