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本文对宫颈癌病人血清88例进行了AG-4抗体(抗HSV-2早期抗原抗体)的检测,其阳性率为72.73％,正常妇女时照组90例,阳性率为51.11％,宫颈癌82例AG-4抗体在放疗前后阳性率无差异,但早期宫颈癌6例,手术切除或中药锥切者,治疗前阳性4例,治疗后2例转为阴性,2例阳性滴度亦下降。宫预癌病人血清的AG-4抗体的几何平均滴度明显高于正常对照组。根据本检测说明HSV-2感染与宫颈癌有一定关系,为此对有HSV-2感染史的妇女,应定期随访,及早发现癌前病变,在临床上有实际意义。
In this paper, 88 cases of cervical cancer patients with AG-4 antibody (anti-HSV-2 early antigen antibody) detection, the positive rate was 72.73%, 90 cases of normal women in the control group, the positive rate was 51.11%, cervical cancer 82 Cases of AG-4 antibody positive rate before and after radiotherapy no difference, but early cervical cancer in 6 cases, surgical resection or conization of Chinese medicine before treatment were positive in 4 cases, 2 cases turned negative after treatment, 2 cases of positive titers also decreased. The mean geometric mean titer of AG-4 antibody in the serum of patients with uterine precancerous lesions was significantly higher than that of the normal control group. According to this test shows that HSV-2 infection and cervical cancer have a certain relationship, for which a history of HSV-2 infection in women should be followed up on a regular basis, early detection of precancerous lesions, clinically meaningful.