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恶性肿瘤合并高凝状态已引起广泛注意,我们曾对肺癌患者凝血状态作过初步观察,半数患者处于高凝状态。本文就蝮蛇抗栓酶改善肺癌高凝状态作一初步探索。 材料与方法 34名有明确病理依据的Ⅲ、Ⅳ期肺癌病人,分为两组:Ⅰ组为抗栓酶治疗组,每天使用抗栓酶2支(0.5酶活力单位),加入5％葡萄糖液500ml静点,持续4h,10天为一疗程;Ⅱ组每天服用潘生丁150mg及复方丹参片9片。抗凝治疗在化疗或放疗前或治疗期间进行,治疗中避免使用其它影响凝血及血液流变性的药物。
Malignant tumor with hypercoagulability state has attracted wide attention, we have made a preliminary observation of coagulation status of patients with lung cancer, half of patients in hypercoagulable state. In this paper, viper antithrombin to improve the hypercoagulability of lung cancer for a preliminary exploration. MATERIALS AND METHODS: Thirty-four patients with stage III and IV lung cancer with definite pathology were divided into two groups: Group I was antithrombotic treatment group. Antithrombotic enzyme (0.5 enzyme activity unit) was used daily, and 5% glucose solution 500ml static point for 4h, 10 days for a course of treatment; group Ⅱ take dipyridamole 150mg daily and compound Danshen tablets 9 tablets. Anticoagulant therapy is performed before or during chemotherapy or radiation therapy and other medications that affect coagulation and blood rheology are avoided during treatment.