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研究发现,金银花的35％乙醇提取物的水溶组分具有显著的预防过敏活性,活性成分之一为绿原酸。金银花的作用机制是抑制iNOS、COX-2表达以及通过抑制TXA2抑制血小板聚集。由于金银花的环烯醚萜组分也具有此活性,故对其成分及作用机制进行了探讨。方法：①生物活性试验：实验动物为ddY系雄性小鼠,以卵白溶菌酶致敏,从致敏日起至第9天,在非麻醉条件下,以激光血流计检测小鼠尾静脉微
It was found that the water-soluble component of the 35% ethanol extract of honeysuckle has a significant preventive activity against allergic reactions, and one of the active ingredients is chlorogenic acid. The mechanism of action of honeysuckle is to inhibit the expression of iNOS, COX-2 and inhibit platelet aggregation by inhibiting TXA2. Since the iridoid component of honeysuckle also has this activity, its composition and mechanism of action are discussed. Methods: 1 Biological activity test: The experimental animals were ddY male mice sensitized with egg white lysozyme. From the day of sensitization to the 9th day, under the non-anesthetic conditions, the mouse tail vein microscopy was measured with a laser blood flow meter.