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[目的]探讨汉族与朝鲜族女性血尿酸水平与代谢相关指标的关系.[方法]对2007年8月—2009年8月间收集的2 775名汉族及朝鲜族女性血样本进行血尿酸水平及代谢相关指标检测.[结果]汉族及朝鲜族女性高尿酸血症粗患病率分别为12.0%,8.6%,标准化患病率分别为10.8%,9.6%,无论粗患病率还是标准化患病率汉族女性的均明显高于朝鲜族女性(P<0.01).汉族女性高尿酸血症患病率随年龄增长呈升高趋势(P<0.01).不同血尿酸水平组间比较见,汉族女性体质指数(BMI)、腰围身高比值(WHtR)、舒张压(DBP)、总胆固醇(TC)及三酰甘油(TG)值间差异均有统计学意义(P<0.01),而朝鲜族女性BMI,WHtR,收缩压(SBP),DBP,TG值间差异均有统计学意义(P<0.01).无论汉族和朝鲜族女性,随着异常代谢综合征组分数目的增加,高尿酸血症的患病率明显升高(P<0.01).本地区女性高尿酸血症的患病与低HDL-C、整体型肥胖、高TC、高TG、高血压和腹型肥胖呈正相关.[结论]汉族女性高尿酸血症患病率明显高于朝鲜族女性;不同血尿酸水平组的代谢指标的分布存在差异;随着代谢综合征组分数的增加,高尿酸血症患病率升高;本地区低HDL-C、整体型肥胖、高TC、高TG、高血压和腹型肥胖与高尿酸血症密切相关.
[Objective] To explore the relationship between serum uric acid level and metabolism-related indicators in Han and Korean women. [Methods] Serum uric acid levels of 2775 Han and Korean female blood samples collected from August 2007 to August 2009 [Results] The crude prevalence rates of hyperuricemia in Han and Korean women were 12.0% and 8.6% respectively, and the standardized prevalence rates were 10.8% and 9.6% respectively, regardless of crude or standardized prevalence Han women were significantly higher than Korean women (P <0.01) .The prevalence of hyperuricemia in Han women increased with age (P <0.01) .The level of serum uric acid was significantly higher in Han women Body mass index (BMI), waist circumference ratio (WHtR), diastolic blood pressure (DBP), total cholesterol (TC) and triglyceride (TG) were significantly different between the two groups (P <0.01) , WHtR, systolic blood pressure (SBP), DBP, TG were significantly different (P <0.01) .Human and Korean women, with the increase of the number of abnormal metabolic syndrome, hyperuricemia The prevalence of hyperuricemia in women in this area was significantly lower than that in women with low HDL-C, generalized obesity, high TC, high TG, hypertension and abdominal obesity were positively correlated. [Conclusion] The prevalence of hyperuricemia in Han women was significantly higher than that of Korean women. There were differences in the distribution of metabolic indexes among different levels of serum uric acid. With the increase of metabolic syndrome components The prevalence of hyperuricemia increased. Low HDL-C, total obesity, high TC, high TG, high blood pressure and abdominal obesity were closely related to hyperuricemia in this area.