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左旋咪唑为四咪唑的左旋体,是一种广谱抗线虫药.1971年 Renoux 曾发现左旋咪唑可激发动物的免疫功能,随后有大量实验室及临床研究证明左旋咪唑可使细胞免疫力原来较低者得到恢复,也能非特异性增加巨噬细胞数,并增强吞噬功能,提高抗感染的抵御能力。Par(1977)曾使用左旋咪唑治疗HBsAg 阳性的乙型肝炎,取得满意的效果。国内也有报道,为进一步观察左旋咪唑对HBsAg 的转阴效果和对免疫指标的影响,曾对7例 HBsAg 阳性的慢性活动型肝炎进行了观察。现报道临床观察结果,以供参考.观察对象本组七例患者,全部 HBsAg 阳性,男性6例,女性1例,病程最短6个月,最长2年。曾使用多种中西医药治疗,无明显效果。入院时除肝功明显障碍外,伴有全身症状及体
Levamisole is a tetrazole levoner, a broad-spectrum anti-nematode drug .1971 Renoux once found that levamisole can stimulate the immune function of animals, followed by a large number of laboratory and clinical studies have shown that levamisole can make the original cellular immunity than The lower recovery, but also non-specific increase in the number of macrophages and enhance phagocytosis, improve the resistance to infection. Par (1977) used levamisole to treat HBsAg-positive hepatitis B and achieved satisfactory results. There are also reports in China. To further observe the effect of levamisole on HBsAg negative effect and immune index, 7 cases of HBsAg positive chronic active hepatitis were observed. Now report the clinical observation results for reference.Observe the seven patients in this group, all HBsAg positive, 6 males and 1 females, the shortest duration of 6 months, up to 2 years. Have used a variety of Chinese and Western medicine treatment, no significant effect. In addition to significant obstruction of liver function on admission, accompanied by systemic symptoms and body