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药物诱发间质性肾炎是急性肾衰的一个常见病因,许多青霉素类抗生素具有此种作用。作者首次报道1例使用邻氯青霉素后出现间质性肾炎的患者。病例:男性,4岁。因发热、烦燥、饮水和排尿减少入院。因足部蜂窝织炎口服邻氯青霉素10d,停药5d后又有发热和表情淡漠,躯干部伴有小红疹。诊断为颈部细菌性淋巴结炎,再次口服邻氯青霉素50mg/kg·d,共7d。但3d后又有发热。入院时有厌食、呕吐和轻度结膜充血,无尿48h。患儿昏睡和
Drug-induced interstitial nephritis is a common cause of acute renal failure, many penicillin antibiotics have this effect. The authors first reported 1 case of patients with interstitial nephritis after the use of cloxacillin. Case: Male, 4 years old. Due to fever, irritability, water and urination reduced admission. Due to foot cellulitis orally oral chlorococcin 10d, 5d after withdrawal there are fever and expression of indifference, accompanied by a small rash of the trunk. Diagnosis of bacterial bacterial lymphadenitis in the neck, again oral chloromycetin 50mg / kg · d, a total of 7d. But after 3d there is fever. Anorexia when hospitalized, vomiting and mild conjunctival hyperemia, anuria 48h. Children drowsiness and sleep