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皮质醇增多症(柯兴综合征)中曾被注意到某些凝血因子浓度的升高。本文报导1例皮质醇增多症伴以弥漫性血管内凝血(DIC)。患者女性、23岁。诉进行性多毛、闭经、腿部易于挫伤和肿张7个月。有严重粉刺、散在的挫伤和眼周及腿部浮肿。血压140/90毫米汞柱。实验室检查:尿正常。电解质测定示明显的低钾性硷中毒。血小板计数持续降低至4000/立方毫米。血红蛋白10克,白细胞7500/立方毫米。上午9时和半夜血浆皮质醇浓度均增高,波动于26和30微克/100毫升之间。尿酮固醇及羟皮质类固醇持续升高,最高值分别为60毫克和109毫克/24小时。X线胸透正常。正考虑作肾上腺切除术时,出现了糖尿,空腹血糖143毫克％。接着
Cortisolism (Cushing’s Syndrome) has been noted in some concentrations of coagulation factors. This article reports 1 case of Cushing’s disease complicated with diffuse intravascular coagulation (DIC). Patient female, 23 years old. V. Progressive hairy, amenorrhea, leg easily bruised and swollen for 7 months. Severe acne, scattered contusion and eye and leg edema. Blood pressure 140/90 mm Hg. Laboratory tests: normal urine. Electrolyte determination showed obvious hypokalemia alkalosis. Platelet count continued to decrease to 4000 / mm3. Hemoglobin 10 grams, white blood cells 7500 / cubic millimeter. Plasma cortisol concentrations increased at 9 am and midnight, with fluctuations between 26 and 30 micrograms per 100 milliliters. Urinary ketones and hydroxy corticosteroids continued to rise, the highest values were 60 mg and 109 mg / 24 hours. X-ray thoracic normal. Being considered for adrenalectomy, there was diabetes, fasting blood sugar 143 mg%. then