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本文采用双盲安慰剂试验评价了Pirmenol治疗室性心律失常的效果。研究对象为17例室性心律失常的病人,其中11例无心脏病,3例为心肌梗塞,2例为轻度主动脉窄狭,1例为肥厚型心肌病。本品给药量顺序为100、150和200mg,每日2次。先给每个病人口服本品100mg每日2次,若室性期前收缩(PVCs)的抑制率小于70%,则增大剂量,直至PVCs的抑制率大于70%。在17例病人中,7例PVCs抑制率大于90%,其中1例无心脏病,6例有心脏病。11例无心脏病病
In this paper, double-blind placebo was used to evaluate the efficacy of Pirmenol in the treatment of ventricular arrhythmias. The subjects were 17 patients with ventricular arrhythmias, 11 without heart disease, 3 with myocardial infarction, 2 with mild narrowing of the aorta and 1 with hypertrophic cardiomyopathy. This product dosage order of 100,150 and 200mg, 2 times a day. First of each oral administration of the product 100mg twice daily, if the ventricular premature contraction (PVCs) inhibition rate of less than 70%, then increase the dose until the PVCs inhibition rate greater than 70%. Among the 17 patients, the inhibition rate of PVCs in 7 cases was more than 90%, of which 1 had no heart disease and 6 had heart disease. 11 cases without heart disease