Agenesis of the dorsal pancreas

• 作 者: Wolfgang J Schnedl Claudia Pis
• 机 构: Practice for General Internal Medicine,Department of Internal Medicine,Institute of Pathophysiology
• 出 处: 世界胃肠病学杂志（英文版）
• 发表日期: 2004年期
• 关键词: Agenesis of dorsal pancreas Diabetes mellitus Glucose intolerance Abdominal pain

During the last 100 years in medical literature, there are only 54 reports, including the report of Pasaoglu et al ( World J Gastroenterol 2008; 14: 2915-2916), with clinical descriptions of agenesis of the dorsal panc reas in humans . Agenes i s of the dor sal pancreas, a rare congenital pancreatic malformation,is associated with some other medical conditions such as hyperglycemia, abdominal pain, pancreatitis and a few other diseases. In approximately 50% of reported patients with this congenital malformation,hyperglycemia was demonstrated. Evaluation of hyperglycemia and diabetes mellitus in all patients with agenesis of the dorsal pancreas including description of fasting blood glucose, oral glucose tolerance test, glycated hemoglobin and medical treatment would be a future goal. Since autosomal dominant transmission has been suggested in single families,more family studies including imaging technologies with demonstration of the pancreatic duct system are needed for evaluation of this disease. With this letter to the editor, we aim to increase available information for the better understanding of this rare disease.