论文部分内容阅读
目的:观察复方苦参注射液联合放射治疗晚期骨转移疼痛的疗效。方法:将我院同期收治住院的骨转移癌患者78例,随机分为对照组38例和治疗组40例。对照组患者采用体外放射治疗(DT30GY,共10次);治疗组在对照组的基础上静脉滴注复方苦参注射液(20mL,每日1次,共10次)。观察治疗后2组患者的骨痛缓解效果、生存质量(KPS)评分和不良反应。结果:治疗组的止痛效果明显优于对照组,2组比较有显著性差异(P<0.01);治疗组KPS评分高于对照组,2组比较有显著性差异(P<0.01);2组患者均未见严重不良反应。结论:复方苦参注射液联合放射治疗晚期骨转移疼痛有明显协同作用,能有效改善患者生存质量。
Objective: To observe the curative effect of compound Kushen injection combined with radiotherapy in treatment of advanced bone metastasis pain. Methods: 78 patients with bone metastases admitted to our hospital in the same period were randomly divided into control group (38 cases) and treatment group (40 cases). The patients in the control group were treated with DT30GY (10 times in total). The treatment group was given Compound Kushen Injection (20mL, once daily for 10 times) on the basis of the control group. The relief of bone pain, quality of life (KPS) score and adverse reactions were observed in two groups after treatment. Results: The analgesic effect of the treatment group was significantly better than that of the control group (P <0.01). The KPS score of the treatment group was higher than that of the control group (P <0.01) No serious adverse reaction in patients. Conclusion: Compound Kushen injection combined with radiotherapy has obvious synergistic effect on the pain of advanced bone metastases, which can effectively improve the quality of life of patients.