论文部分内容阅读
目的了解东莞市2009-2010年手足口病疫情的流行病学特点,为今后的防控工作提出对策。方法对东莞市2009-2010年手足口病疫情资料采用描述流行病学方法进行分析,对患者的咽拭子或粪便标本采用RT-PCR法进行肠道病毒核酸检测和病毒分型。结果东莞市2009年和2010年分别报告手足口病9263例和22721例,发病率分别为127.34/10万和373.28/10万。5岁以下婴幼儿分别占当年报告病例的91.68%和92.15%;散居儿童分别占当年报告病例的78.26%和73.58%;男性分别占当年报告病例的65.29%和65.27%;每年的4月份和10月份有2个发病高峰,前者为全年的发病高峰;暴发疫情均发生在托幼机构;分别有49.30%和53.65%的病例由EV71引起,所有死亡病例均由EV71引起。健康人群肠道病毒隐性感染率为11.67%,感染的主要病原体为其他肠道病毒(95.24%)。结论东莞市2010年手足口病流行强度大于2009年;应重点做好手足口病的病原学监测及5岁以下散居儿童和托幼机构的手足口病防治工作。
Objective To understand the epidemiological characteristics of HFMD in Dongguan from 2009 to 2010 and to put forward countermeasures for future prevention and control. Methods Epidemiological data of hand, foot and mouth disease outbreaks in Dongguan from 2009 to 2010 were analyzed. The throat swabs or stool samples of patients were tested by RT-PCR for detection of enterovirus nucleic acid and typing of viruses. Results In 2009 and 2010, Dongguan reported 9263 cases of HFMD and 22,721 cases of HFMD respectively, the incidence rates were 127.34 / 100000 and 373.28 / 100000 respectively. Infants under 5 accounted for 91.68% and 92.15% respectively of the reported cases for the year; scattered children accounted for 78.26% and 73.58% of the reported cases respectively; men accounted for 65.29% and 65.27% of the reported cases respectively; and in April and 10 There were two peaks in the month. The former was the peak of the year. The outbreaks occurred in the nurseries; 49.30% and 53.65% of the cases were caused by EV71 respectively, and all the deaths were caused by EV71. The latent infection rate of enterovirus in healthy population was 11.67%, and the main pathogen of infection was other enterovirus (95.24%). Conclusion The prevalence of hand, foot and mouth disease in Dongguan in 2010 is greater than that of 2009; etiopathogenisis of hand-foot-mouth disease and hand-foot-mouth disease prevention and control in diaspora and kindergarten under 5 years old should be emphasized.