Erythrocytosis caused by giant chromophobe renal cell carcinoma:a case report indicating a 9-year mi

• 作 者: Renbo Guo Yiran Liang Lei Yan Zhonghua Xu Juchao Ren
• 机 构: Department of Urology,Shandong Cancer Hospital Affiliated to Shandong University,Department of Breas
• 出 处: Chinese Journal of Cancer
• 发表日期: 2017年09期
• 关键词: giant Secondary attributed presentation young pathologic suffering postoperative

Background:Erythrocytosis,a rare paraneoplastic syndrome,generally occurs in patients with clear cell renal cell carcinoma and has never been reported in patients with chromophobe renal cell carcinoma.Case presentation:We report a case of a young man suffering from a giant(22-cm) mass on his left kidney.Because of a history of polycythemia vera,the patient had been treated for the condition for 9 years.Radical nephrectomy was successfully performed,and the postoperative pathologic examination confirmed a diagnosis of chromophobe renal cell carcinoma.Unexpectedly,the symptom of erythrocytosis disappeared after the surgery.Further examination and analysis were performed,and we finally attributed his erythrocytosis to chromophobe renal cell carcinoma.Conclusions:Chromophobe renal cell carcinoma could cause erythrocytosis,but the clear-cut mechanism needs further research.Secondary erythrocytosis such as those related with renal tumors should be taken into consideration during the diagnosis of polycythemia vera.

Background: Erythrocytosis, a rare paraneoplastic syndrome, generally occurs in patients with clear cell renal cell carcinoma and has never been reported in patients with chromophobe renal cell carcinoma. Case presentation: We report a case of a young man suffering from a giant (22- cm) mass on his left kidney.Because of a history of polycythemia vera, the patient had been treated for the condition for 9 years. Radical nephrectomy was successfully performed, and the postoperative pathologic confirmation confirmed a chromophobe renal cell carcinoma. Unexpectedly, the symptom of erythrocytosis disappeared after the surgery. Focus examination and analysis were performed, and we finally attributed his erythrocytosis to chromophobe renal cell carcinoma. Conclusions: Chromophobe renal cell carcinoma could cause erythrocytosis, but the clear-cut mechanism needs further research. Secondary erythrocytosis such as those those related with renal tumors should be taken into consideration during the diagnosi s of polycythemia vera.