Single-cell sequencing delivers hematopoietic stem cell specification

• 作 者: Jiani Cao Tongbiao Zhao
• 机 构: StateKeyLaboratoryofStemCellandReproductiveBiology
• 出 处: 中国科学通报：英文版
• 发表日期: 2016年18期
• 关键词: 造血干细胞 单细胞 测序 HSC 细胞分化 分辨率 扩展性 小鼠
• 基金项目: This work was supported by the National Basic Research Program of China （2013CB966901）, the Strategic Priority Research Program of the Chinese Academy of Sciences （XDA01040108）, and the National Natur

<正>Recently,Zhou et al.[1]have successfully traced the hematopoietic stem cell(HSC)specification during the stepwise development of HSC from the pre-HSC stage at single-cell resolution.These findings offer fundamental insights into mouse HSC fate de