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目的:通过对257例出生缺陷的分析,了解该地区出生缺陷的发生及干预措施情况。方法:对2004～2010年在该院住院分娩的妊娠妇女15 926例,分娩缺陷儿257例进行临床分析。结果:出生缺陷发生率为16.14‰,各年出生缺陷发生率比较有统计学差异(P<0.01),近年出生缺陷发生率有增高趋势;出生缺陷儿死亡160例,占围产儿死亡总数的70.48%;出生缺陷顺位前5位为:巴氏水肿、唇裂、多指、脑积水、脐膨出、无脑儿。结论:加强孕妇的健康教育,普及预防出生缺陷的相关知识,及早发现、及时干预是降低出生缺陷发生率的主要途径,而提高对做好孕前保健重要性的认识,加强孕期保健则是政府和医院的重要课题。
Objective: To analyze the incidence of birth defects in 257 cases and the intervention measures in this area. Methods: 15 926 pregnant women and 257 childbirth defective children who were hospitalized in the hospital from 2004 to 2010 were analyzed. Results: The incidence of birth defects was 16.14 ‰, and the incidence of birth defects in each year was statistically significant (P <0.01). The incidence of birth defects in recent years had an increasing trend. Birth defects accounted for 160 cases, accounting for 70.48% of the total number of perinatal deaths %; Birth defects in the top 5: Pap edema, cleft lip, multi-finger, hydrocephalus, umbilical swelling, no brain children. CONCLUSIONS: Strengthening the health education of pregnant women, popularizing the knowledge of prevention of birth defects, early detection and prompt intervention are the main ways to reduce the incidence of birth defects, and raising the awareness of the importance of pre-pregnancy health care. Hospital’s important topic.