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目的了解我国一般人群血液中锑元素的含量水平,并分析其人群分布特点,建立我国一般人群生物样本中锑元素含量参考值和横断面基础数据。方法在2009-2010年间采用分层抽样的方法,从东、中、西部3个地区抽取8个省(自治区、直辖市),共完成18 120名调查对象的全血样品的采集。应用电感藕合等离子体质谱法检测血液中锑元素的含量,比较分析我国一般人群血液中锑元素含量在不同年龄、性别中的分布特征。结果我国一般人群血液中锑元素含量中位数为3.46μg/L,其中男性为3.42μg/L,女性为3.48μg/L,在性别间的差异无统计学意义(χ2=2.62;P>0.05)。锑元素含量随年龄增长呈下降趋势且差异有统计学意义(χ2=35.98;P<0.01)。我国人群血液中锑元素含量明显高于国外相关报道。结论自大样本测定、提供了我国一般人群中锑元素含量的可靠数据,也是评估环境污染的一个参考。
Objective To understand the level of antimony in the blood of general population in our country and to analyze its population distribution characteristics and to establish the reference value of antimony content and basic data of cross section in biological samples of general population in our country. Methods By stratified sampling from 2009 to 2010, 8 provinces (autonomous regions and municipalities directly under the Central Government) were drawn from 3 regions of eastern, central and western China. A total of 18 120 whole blood samples were collected. The content of antimony in blood was detected by inductively coupled plasma mass spectrometry, and the distribution characteristics of antimony in blood were analyzed in different age and sex in our country. Results The median antimony content in the blood of our general population was 3.46 μg / L, with 3.42 μg / L for males and 3.48 μg / L for females, with no significant difference in gender (χ2 = 2.62; P> 0.05 ). The content of antimony decreased with age and the difference was statistically significant (χ2 = 35.98; P <0.01). Chinese people’s blood antimony content was significantly higher than foreign reports. Conclusion The determination of self-inflated samples provides reliable data on the antimony content of the general population in China and is also a reference for assessing environmental pollution.