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目的:观察桐油调入中药外敷联合阿昔洛韦治疗带状疱疹的临床疗效及免疫功能的影响。方法:将70例带状疱疹患者随机分为2组各35例,对照组单纯行阿昔洛韦治疗,观察组在对照组的基础上予桐油调入中药外敷治疗,观察2组治疗后皮损恢复效果及对机体免疫功能的变化。结果:总有效率观察组为94.29%,对照组为77.14%,2组比较,差异有统计学意义(P<0.05)。2组治疗后CD8+均较治疗前升高(P<0.05),且观察组CD8+升高较对照组更显著。治疗后观察组CD4/CD8较治疗前及对照组治疗后降低,差异均有统计学意义(P<0.05)。结论:桐油调入中药外敷联合阿昔洛韦治疗带状疱疹,能显著改善患者皮损状况;但其对机体免疫功能有一定影响。
Objective: To observe the clinical efficacy and immune function of tung oil transferred to traditional Chinese medicine combined with acyclovir in the treatment of shingles. Methods: Seventy patients with herpes zoster were randomly divided into two groups of 35 cases. The control group was treated with acyclovir only. The observation group was treated with tung oil on the basis of the control group, Damage recovery effect and changes of immune function. Results: The total effective rate was 94.29% in the observation group and 77.14% in the control group. There was significant difference between the two groups (P <0.05). CD8 + in both groups were significantly higher than those before treatment (P <0.05), and the increase of CD8 + in the observation group was more significant than that in the control group. After treatment, CD4 / CD8 in observation group was lower than that before treatment and in control group after treatment, the difference was statistically significant (P <0.05). Conclusion: Tung oil transferred to traditional Chinese medicine combined with acyclovir in the treatment of shingles, can significantly improve the patient’s skin lesions; but it has some impact on the immune function.