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1,3-双〔-4′-(7′-氯喹啉基)哌嗪基〕丙烷(以下简称哌喹)是国内外用于防治疟疾效果较好的药物,有口服、长效及副作用小的优点。为了研究喹啉环上不同的取代卤素对药理作用的影响,以及研究哌喹类药物
1,3-Bis [-4 ’- (7’-chloroquinolyl) piperazinyl] propane (hereinafter referred to as piperaquine) is a good domestic and foreign drug for the prevention and treatment of malaria with oral, long-term and side effects advantage. In order to study the effect of different substituted halides on the pharmacological effects of quinolines,