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本文选择20例经支气管镜证实的气管或主支气管癌病人,由于不宜手术治疗而在全麻下采用了二氧化碳激光切除。11例病人于激光治疗前曾用过放射治疗。病人气道阻塞的严重性是根据FEV_1、最大吸气和最大呼气流量-容积曲线(MIFV 和MEFV)、最大呼气流量(PEF),以及50%肺活量最大呼气和吸气流量(V_((?)0)评定。用标记0(未完全屏息)～100mm(完全屏息)的模拟尺记分,评估病人屏气状态。20例病人中13例为单侧病变并伴有主支气管的部分或完全阻塞。用~(99m)Tc 或~(133)Xe 进行了放射性同位素肺扫描,以观察肺灌注-通气的变化。结果激光治疗10天FEV_1从预计值的51.9%提高到62.6%(p<0.02),平均PEF 从预计值的
In this paper, 20 cases of patients with tracheobronchial or bronchogenic carcinoma confirmed by bronchoscopy were selected, and CO2 laser ablation was performed under general anesthesia due to unfit surgical treatment. Eleven patients had been treated with radiation before laser treatment. The severity of airway obstruction in patients was based on FEV 1, maximal inspiratory and maximal expiratory flow-volume curves (MIFV and MEFV), maximal expiratory flow (PEF), and maximal expiratory and inspiratory flow at 50% (0) .Evaluation of the patient’s breath holding state was scored using a simulated scale marked 0 (incomplete breath-hold) ~ 100 mm (complete breath-hold). Of the 20 patients, 13 were unilateral lesions with partial or complete bronchus (99m) Tc or ~ (133) Xe was used to observe lung perfusion-ventilation changes.Results The FEV_1 increased from 51.9% of predicted value to 62.6% at 10 days after laser treatment (p <0.02 ), The average PEF from the expected value