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目的探讨老年慢性鼻窦炎和鼻息肉患者血脂水平的变化。方法 42例慢性鼻窦炎和鼻息肉患者作为治疗组,别选择45例门诊患者作为正常对照组,均行多导睡眠监测(PSG)检查,空腹抽取静脉血测定血脂水平,并对治疗组患者行鼻内窥镜手术,将术后6个月的相关检查指标与术前比较。结果治疗组患者术前血中总胆固醇(TC)、甘油三酯(TG)、低密度脂蛋白胆固醇(LDL-C)、载脂蛋白B(APO-B)均高于对照组(P<0.05),高密度脂蛋白(HDL)低于对照组,但差异无统计学意义。手术治疗6个月后,TC、TG、LDL-C、APO-B值明显减少,HDL明显增高,差异有统计学意义(P<0.05)。结论老年慢性鼻窦炎和鼻息肉与血脂代谢紊乱有一定相关性,手术治疗有助于纠正慢性鼻窦炎和鼻息肉患者的脂代谢紊乱。
Objective To investigate the changes of blood lipid levels in elderly patients with chronic sinusitis and nasal polyps. Methods Forty - two patients with chronic sinusitis and nasal polyps were enrolled as treatment group. Forty - five outpatients were selected as normal control group. All patients underwent polysomnography (PSG) and fasting venous blood samples were collected for blood lipid analysis. Patients in treatment group Nasal endoscopic surgery, the postoperative 6 months of related indicators and preoperative comparison. Results The preoperative blood TC, TG, LDL-C and APO-B in the treatment group were significantly higher than those in the control group (P <0.05 ), High-density lipoprotein (HDL) lower than the control group, but the difference was not statistically significant. The levels of TC, TG, LDL-C and APO-B decreased significantly after 6 months of operation, and the HDL increased significantly. The difference was statistically significant (P <0.05). Conclusion Senile chronic sinusitis and nasal polyps have some correlation with dyslipidemia, and surgical treatment can help to correct the disorder of lipid metabolism in patients with chronic sinusitis and nasal polyps.