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目的 :探讨99mTc -甲氧基异丁基异腈(MIBI)阳性显像诊断头颈部肿瘤的临床价值。材料和方法 :对53例经病理证实的头颈部恶性肿瘤、良性肿瘤和炎症进行99m Tc -MIBI平面和/或断层显像。结果 :37例恶性肿瘤 ,35例显像为阳性 ;16例良性病变 ,13例显像为阴性 ,敏感性为94 6 % ,特异性为81 3 % ,准确性为90 6 %。37例恶性肿瘤中 ,16例喉癌病人病理证实无淋巴结转移 ,显像中淋巴结均为阴性 ;12例有淋巴结转移者 ,7例淋巴结显像为阳性 ,敏感性为58 3 % ,特异性为100 % ,准确性为82 1 %。结论 :99mTc-MIBI头颈部肿瘤阳性显像简便无创 ,在头颈部病变的定性诊断中具有一定的临床价值。可为临床的病变分期、手术术式的选择、治疗方案的制定等提供有力依据
Objective: To investigate the clinical value of 99mTc - methoxyisobutyl isonitrile (MIBI) positive imaging in the diagnosis of head and neck cancer. Materials and Methods: 99m Tc-MIBI planar and / or tomographic images of 53 pathologically confirmed head and neck malignancies, benign tumors and inflammation were performed. Results: Thirty-seven cases of malignant tumors were positive in 35 cases. In 16 cases of benign lesions, 13 cases were negative, with sensitivity of 94.6%, specificity of 81.3% and accuracy of 90.6%. Of the 37 malignant tumors, 16 cases of laryngeal carcinoma showed no lymph node metastasis and no lymph nodes were found in the pathology. Among 12 cases with lymph node metastasis and 7 cases with lymph node metastasis, the sensitivity was 58.3% and the specificity was 100%, accuracy of 82 1%. Conclusion: 99mTc-MIBI positive and negative imaging of head and neck tumors is simple and noninvasive, and has certain clinical value in the qualitative diagnosis of head and neck lesions. Can provide a strong basis for the clinical stage of the disease, the choice of surgical procedures, the development of treatment options