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研究了白银矿区周围绵羊以消瘦和贫血为主要特征的疾病。通过检测食物链系统及绵羊全血、被毛和组织器官中１３种矿物元素（Ｐｂ、Ｃｄ、Ｚｎ、Ｆｅ、Ｍｎ、Ｍｏ、Ｃｕ、Ｆ、Ａｓ、Ｓｅ、Ａｌ、Ｃａ、Ｐ）的含量，分析血液生理生化指标的变化，揭示出现地牧草中Ｐｂ、Ｃｄ的含量高，分别为（１１１．２±９８．４）μｇ／ｇ和（１２．０±１．２）μｇ／ｇ；动物体内的Ｐｂ、Ｃｄ沉积量亦极显著高于允许值（Ｐ＜０．０１）；动物呈低色素小细胞性贫血，血清ＬＤＨ、ＡＬＴ活性和Ｔ３含量显著升高（Ｐ＜０．０１），血清蛋白含量降低（Ｐ＜０．０１），以及实质器官变性、坏死，肾小管上皮细胞核包涵体等病理学特点。确认该病系工业环境污染所致的绵羊铅镉联合中毒
The disease characterized by weight loss and anemia in sheep around silver mines was studied. The contents of 13 mineral elements (Pb, Cd, Zn, Fe, Mn, Mo, Cu, F, As, Se, Al, Ca, P) in the food chain system, sheep whole blood, The change of blood physiological and biochemical indexes revealed that the contents of Pb and Cd in the forage grass were high (111.2 ± 98.4) μg / g and (12.0 ± 1.2) μg / g, respectively (P <0.01). The animals showed hypochromic small cell anemia, the activities of serum LDH, ALT and T3 were significantly increased (P <0.01), while the contents of serum albumin (P <0.01), as well as pathological features of degeneration and necrosis of the essential organs and nuclear inclusions in renal tubular epithelial cells. Confirmed that the disease is caused by industrial environmental pollution of sheep lead cadmium poisoning