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本文主要研究柯萨奇B_4病毒和脑心肌炎病毒(EMC病毒)对冠状动脉和主动脉的损害。作者用含柯萨奇B_4病毒(滴度为10~(-3)~10~(-5)TCID50)的猴肾细胞培养液或含EMC病毒(滴度为10~(-6)TCID50)的L-细胞培养物0.025~0.1毫升接种于小白鼠腹腔。接种后24小时至10天内杀死小白鼠,立即采取标本,用光学和电子显微镜观察。作者发现,柯萨奇B_4病毒和EMC病毒不仅引起心肌病,而且使心肌毛细血管、冠状动脉、主动脉
This article focuses on Coxsackie B virus and encephalomyocarditis virus (EMC virus) on the coronary and aortic damage. Using monkey kidney cell culture containing Coxsackie virus B_4 (titers of 10 -3 to 10 -5 TCID50) or EMC virus (titer of 10 -6 TCID 50) L-cell culture 0.025 ~ 0.1 ml inoculated in the abdominal cavity of mice. Mice were sacrificed within 24 hours to 10 days after inoculation, specimens were taken immediately and examined by light and electron microscopy. The authors found that Coxsackie B_4 virus and EMC virus not only cause cardiomyopathy, but also make the myocardium capillaries, coronary arteries, aorta