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目的观察和评价酪酸梭菌活菌散治疗手足口病的临床疗效。方法将34例手足口病患儿随机分为治疗组和对照组,治疗组18例,对照组16例,2组均给予对症支持治疗。其中治疗组在治疗的同时加用酪酸梭菌活菌散,1周岁以下,0.5g/次,1周岁以上,1g/次,3次/d,温水送服。对照组不用酪酸梭菌活菌散治疗。对两组疱疹、食欲、体温变化情况及腹泻等并发症进行统计分析。结果治疗组起效时间、疱疹消失时间、食欲正常时间和体温恢复正常时间显著短于对照组,差异具有统计学意义(P<0.05或0.01)。结论酪酸梭菌活菌散治疗手足口病疗效显著,具有积极的临床意义。
Objective To observe and evaluate the clinical efficacy of Clostridium butyricum in the treatment of hand, foot and mouth disease. Methods 34 cases of hand, foot and mouth disease were randomly divided into treatment group and control group, 18 cases in the treatment group and 16 cases in the control group. Both groups were given symptomatic and supportive treatment. The treatment group in the treatment of Clostridium plus Clostridium difficile, less than 1 year old, 0.5g / time, 1 year old, 1g / time, 3 times / d, warm water delivery service. The control group did not Clostridium butyricum live bacteria treatment. The two groups of herpes, appetite, temperature changes and diarrhea and other complications were statistically analyzed. Results The onset time, herpes disappearance time, normal appetite time and body temperature recovery time in the treatment group were significantly shorter than those in the control group, the difference was statistically significant (P <0.05 or 0.01). Conclusion Clostridium butyricum is the treatment of hand, foot and mouth disease with significant efficacy, with a positive clinical significance.