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目的:通过对中西医结合治疗单纯疱疹病毒性角膜炎的临床观察,评价其临床疗效及安全性。方法:随机选取符合研究标准的单纯疱疹病毒性角膜炎的病例,随机分为治疗组和对照组。治疗组应用中西医结合治疗,口服院内自制中药制剂菊兰清明片或谷龙清明片+西药。对照组单纯应用西药治疗。共连续治疗3周。结果:治疗组治愈率为76.7%,有效率为20%,总有效率为96.7%;对照组治愈率为61.7%,有效率为21.6%,总有效率为83.3%。经统计学处理,两组之间的治愈率和总有效率有显著性差异(P<0.05)。治疗组平均治愈时间短于对照组。治疗组明显优于对照组。治愈病例均随访1年,治疗组无复发:对照组复发10例,占对照组治愈病人的27%。结论:中西医结合治疗单纯疱疹病毒性角膜炎疗效优于单纯西医治疗,疗程短,见效快,减少复发。
Objective: To evaluate the clinical efficacy and safety of herpes simplex keratitis by combining traditional Chinese and Western medicine. Methods: Randomly selected cases of herpes simplex virus keratitis that meet the research criteria were randomly divided into treatment group and control group. Treatment group with Integrative Medicine treatment, oral self-made in-hospital preparations of Chrysanthemum Ching Ming or Gu Long Qing Ming + Western medicine. The control group was treated with western medicine alone. A total of 3 consecutive weeks of treatment. Results: The cure rate of the treatment group was 76.7%, the effective rate was 20% and the total effective rate was 96.7%. The cure rate of the control group was 61.7%, the effective rate was 21.6% and the total effective rate was 83.3%. Statistically, there was a significant difference between the two groups in the cure rate and the total effective rate (P <0.05). The mean healing time of the treatment group was shorter than that of the control group. The treatment group was significantly better than the control group. The cured cases were followed up for 1 year. The treatment group had no relapse: the control group recurred in 10 cases, accounting for 27% of the cured patients in the control group. Conclusion: Integrative treatment of herpes simplex virus keratitis is superior to Western medicine treatment alone, short course, quick, reduce recurrence.