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目的研究儿童重症手足口病的临床特征,为早期临床诊断提供依据。方法选取安阳市第五人民医院46例儿童重症手足口病患儿的临床资料,回顾性分析其临床诊断及临床特征。结果主要临床特征如下:皮疹及口腔溃疡46例(100%),高热45例(97.8%),中枢神经系统(CNS)症状35例(76.1%),呼吸急促24例(52.2%),支气管炎8例(17.4%),咳嗽17例(37.0%),肺水肿7例(15.2%),消化系统症状27例(58.7%),EV71感染者35例(76.1%)。结论儿童重症手足口病发病急,病情发展快,加强研究其临床特征有利于早期识别和处理危重病例,对降低病死率、改善患者预后有重要意义。
Objective To study the clinical features of severe hand-foot-mouth disease in children and provide the basis for early clinical diagnosis. Methods The clinical data of 46 children with severe hand-foot-mouth disease in Children’s Hospital of Anyang City were selected. The clinical diagnosis and clinical features were retrospectively analyzed. Results The main clinical features were as follows: 46 cases (100%) of rash and mouth ulcers, 45 cases (97.8%) of fever, 35 cases (76.1%) of central nervous system (CNS) symptoms, 24 cases (52.2%) of shortness of breath, bronchitis 8 cases (17.4%), 17 cases of cough (37.0%), 7 cases of pulmonary edema (15.2%), 27 cases of digestive system symptoms (58.7%) and 35 cases (76.1%) of EV71 infection. Conclusions The incidence of severe HFMD in children is acute and the disease progresses rapidly. To study more about its clinical features is beneficial to early identification and treatment of critically ill children, which is of great importance in reducing mortality and improving the prognosis of patients.