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目的：研究新疆哈萨克族人群STK39基因rs3754777多态性与原发性高血压的关系。方法通过流行病学调查获得新疆哈萨克族原发性高血压患者300例(高血压组)，健康对照组300例，采用TaqMan探针法分析STK39基因rs3754777多态性的基因型。结果高血压组与对照组STK39基因rs3754777G/A多态性差异无统计学意义。结论 STK39基因rs3754777G/A多态性与新疆哈萨克族原发性高血压无相关性。“,”Objective To study the relationship between rs3754777 polymorphisms in STK39 gene and essential hypertension in Kazak population in Xinjiang. Methods Through epidemiological survey in Xinjiang Kazak population, 300 cases were as essential hypertension group and 300 cases as normal control group. TaqMan probe method was used to analysis the rs3754777 polymorphism genotype in STK39 gene. Results Tht rs3754777 G/A polymoiphism in STK39 gene had no significant dif erence between two groups. Conclusion The essential hypertension in Kazak in Xinjiang is not associated with rs3754777 G/A polymorphism of STK39 gene.