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目的了解肺癌患者抗菌药物临床使用情况,为合理用药提供参考。方法回顾性调查2009年1月-2011年12月209例肺癌患者病例资料,对抗菌药物使用各项数据进行分析。结果 209例患者抗菌药物使用率为39.71%,其中单一用药占49.40%;病原菌送检比率为31.33%;用药以β-内酰胺类为主,其中头孢菌素使用频次最高,限制使用和特殊使用品种比例分别为28.66%和43.90%。结论抗菌药物使用总体较合理,但限制和特殊使用品种、用量偏多,病原菌送检及药敏试验比率较低,需进一步加强抗菌药物的使用管理。
Objective To understand the clinical use of antimicrobial agents in patients with lung cancer and provide reference for rational drug use. Methods The data of 209 lung cancer patients from January 2009 to December 2011 were retrospectively analyzed. The data of antimicrobial agents were analyzed. Results The usage of antibacterials in the 209 patients was 39.71%, accounting for 49.40% for single drug and 31.33% for the pathogenic bacteria. The drugs used were mainly β-lactams, of which cephalosporins were the most frequently used, restricted and special The proportion of varieties were 28.66% and 43.90% respectively. Conclusion The overall use of antimicrobial agents is more reasonable. However, the restricted and specially used varieties, the higher dosage, the lower rate of pathogenic bacteria submission and susceptibility testing, and the further use and management of antimicrobial agents are needed.