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A novel potassium complex KC9H9NO4SBr has been synthesized and characterized by IR spectra and single-crystal X-ray diffraction method. The crystal belongs to orthorhombic, space group Pbca with a = 0.74040(15), b = 0.74960(15), c = 4.2620(9) nm, V = 2.3654(8) nm3, Mr = 346.24, Dc = 1.945 g/cm3, Z = 8, F(000) = 1376, μ(MoKa) = 4.005mm-1, GOOF = 1.021, R = 0.0471 and wR = 0.0872. In the crystal, the potassium ion is typically eight-coordinated, surrounded by eight O atoms from six (E)-2-(5-bromo-2-hydroxy-benzyli-deneamino)ethane- sulfonate anions. The neighboring potassium ions are bridged by sulfonate groups into a two-dimensional layer structure, above and below which the 5-bromo-2-hydroxy-benzene rings are protruded. The activity against acetaminophen-induced hepatotoxicity of this complex was also studied, and found it can protect liver from hepatotoxicity induced by acetaminophen (AAP) to some extent.
A novel potassium complex KC9H9NO4SBr has been synthesized and characterized by IR spectra and single-crystal X-ray diffraction method. The crystal belongs to orthorhombic space group Pbca with a = 0.74040 (15), b = 0.74960 (15), c = (9) nm V = 2.3654 (8) nm3 Mr = 346.24 Dc = 1.945 g / cm3 Z = 8 F000 = 1376 μ MoKa = 4.005 mm-1 GOOF = 1.021 R = 0.0471 and wR = 0.0872. The crystal of the potassium ion is typically eight-coordinated, surrounded by eight O atoms from six (E) -2- (5-bromo-2- hydroxy-benzyli-deneamino) ethane- sulfonate anions The surrounding potassium ions are bridged by sulfonate groups into a two-dimensional layer structure, above and below which the 5-bromo-2-hydroxy-benzene rings are protruded. The activity against acetaminophen-induced hepatotoxicity of this complex was also studied, and found it can protect liver from hepatotoxicity induced by acetaminophen (AAP) to some extent.