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目的:总结心尖肥厚型心肌病的临床特征及治疗方法。方法:回顾性分析我院2008年6月至2012年2月期间经心脏超声或左室造影证实的33例心尖肥厚型心肌病患者的临床特征及治疗情况。结果:患者的临床症状表现为以胸闷、气短为主者20例;心前区不适4例;心前区疼痛5例;乏力2例;心悸1例;发现心电图异常前来就诊1例。32例患者行左室造影诊断为心尖肥厚型心肌病。1例因肾功能不全,未行左室造影,但经心脏超声诊断为心尖肥厚型心肌病。27例患者服用β-受体阻滞剂,2例患者服用钙离子拮抗剂,4例患者因心率慢,未服用药物,临床随访1～36(平均16.7±4.1)个月,临床症状均明显缓解。结论:β-受体阻滞剂和钙离子拮抗剂均适用于治疗心尖肥厚型心肌病。
Objective: To summarize the clinical features and treatment of apical hypertrophic cardiomyopathy. Methods: The clinical features and treatment of 33 patients with apical hypertrophic cardiomyopathy confirmed by echocardiography or left ventricular angiography in our hospital from June 2008 to February 2012 were retrospectively analyzed. Results: The clinical manifestations of patients with chest tightness, shortness of breath mainly in 20 cases; precordial discomfort in 4 cases; anterior chamber pain in 5 cases; fatigue in 2 cases; palpitations in 1 case; found abnormal electrocardiogram came to the clinic in 1 case. 32 patients underwent left ventricular angiography diagnosis of apical hypertrophic cardiomyopathy. 1 case of renal insufficiency, left ventricular angiography was not performed, but the diagnosis of apical hypertrophic cardiomyopathy by echocardiography. 27 patients taking β-blockers, 2 patients taking calcium antagonists, 4 patients due to slow heart rate, no medication, clinical follow-up 1-36 (average 16.7 ± 4.1) months, the clinical symptoms were significantly ease. Conclusion: Both β-blockers and calcium antagonists are suitable for the treatment of apical hypertrophic cardiomyopathy.