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目的探讨影响宫颈癌放疗疗效的预后因素。方法1984年5月至1992年12月收治宫颈癌 66例,其中手术加放疗10例;腔内后装放疗加~(60)Co外照射 6例;~(60)Co外照射25例,~(60)Co加体腔筒外照射25例。结果 治疗后的3年、5年生存率分别为57.58%、46.97%。Ⅰ、Ⅱ、Ⅲ、Ⅳ期的5年生存率分别为100%(2/2)、70%(14/20)、35.71%(15/42)、0(0/2),Ⅱ期与Ⅲ期有显著性差别。放疗剂量<60Gy和60~70Gy的5年生存率分别为13.33%、48.57%(P<0.05);放疗结束肿瘤完全消失与部分消失的5年生存率分别为 58.33%、10%(P<0.01)。结论 分期愈早,预后愈好,放射治疗剂量以 60~70Gy为佳,放疗结束时肿瘤完全消失预后较好。
Objective To investigate the prognostic factors of cervical cancer radiotherapy. Methods From May 1984 to December 1992, 66 cases of cervical cancer were treated, including surgery and radiotherapy in 10 cases; intracavitary posterior radiation plus radiotherapy (60Co) in 6 cases; radiotherapy of ~ (60) Co in 25 cases, (60) Co plus lumen external irradiation in 25 cases. Results The 3-year and 5-year survival rates after treatment were 57.58% and 46.97% respectively. The 5-year survival rates of stage Ⅰ, Ⅱ, Ⅲ and Ⅳ were 100% (2/2), 70% (14/20), 35.71% (15/42), 0 (0/2) There was a significant difference with stage Ⅲ. The 5-year survival rates of radiotherapy doses <60 Gy and 60-70 Gy were 13.33% and 48.57%, respectively (P <0.05). The 5-year survival rates of complete disappearance and partial disappearance of tumors after radiotherapy were 58.33 %, 10% (P <0.01). Conclusions The earlier the staging, the better the prognosis, radiation dose 60 ~ 70Gy better, completely disappeared at the end of radiotherapy prognosis is good.