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目的:分析海南省围产儿出生缺陷的基本情况及动态变化,探索影响围产儿出生缺陷的原因及预防策略。方法:对2005~2010年海南省某妇幼保健院出生缺陷围产儿的资料进行统计分析。结果:11 483例围产儿中发生出生缺陷286例,出生缺陷发生率为24.91‰;出生缺陷儿死亡率为3.57‰。出生缺陷前5位疾病是:唇腭裂、多指畸形、外耳畸形、先天性心脏病、神经管发育畸形;出生缺陷发生率与孕产妇年龄呈正相关,年龄35岁以上是发生出生缺陷的高危因素;分娩出生缺陷新生儿的孕妇以城乡低收入、低文化人群为主。结论:加强育龄孕妇产前筛查和优生优育教育,营造优生优育的社会和文化环境,降低婴儿出生缺陷的发生率。
Objective: To analyze the basic situation and dynamic changes of birth defects in perinatal children in Hainan Province and to explore the causes and prevention strategies of birth defects in perinatal children. Methods: The data of birth defects in a maternity and child care hospital in Hainan Province from 2005 to 2010 were analyzed statistically. Results: There were 286 cases of birth defects in 11 483 cases of perinatal birth, the incidence of birth defects was 24.91 ‰, and the mortality rate of birth defects was 3.57 ‰. The top 5 birth defects were: cleft lip and palate, multiple deformities, external ear deformities, congenital heart disease, neural tube deformity; the incidence of birth defects and maternal age was positively correlated with the age of 35 years of age is the risk of birth defects ; Pregnant women with birth defects neonatal low income, low-cultural population-based. Conclusion: To strengthen prenatal screening and prenatal and postnatal care of pregnant women, to create a social and cultural environment for prenatal and postnatal care and to reduce the incidence of infant birth defects.