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目的观察前列地尔注射液联合丹参酮ⅡA磺酸钠注射液治疗后循环缺血性眩晕的临床疗效。方法将我院收治的56例后循环缺血性眩晕患者随机分为治疗组30例和对照组26例,在常规治疗的基础上,治疗组给予前列地尔联合丹参酮ⅡA磺酸钠注射液治疗,对照组仅给予丹参酮ⅡA磺酸钠注射液治疗,10d为1个疗程。结果治疗组总有效率为96.7%,高于对照组的84.6%,差异有统计学意义(P<0.05);两组均未出现明显不良反应,治疗耐受性好。结论前列地尔注射液联合丹参酮ⅡA磺酸钠注射液治疗后循环缺血性眩晕疗效优于单用丹参酮ⅡA磺酸钠注射液治疗,且不良反应少,值得临床推广。
Objective To observe the clinical efficacy of alprostadil injection plus tanshinone Ⅱ A sodium sulfonate injection in treatment of ischemic vertigo. Methods Fifty-six patients with posterior circulation ischemic vertigo treated in our hospital were randomly divided into treatment group (n = 30) and control group (n = 26). On the basis of conventional treatment, the treatment group was given alprostadil combined with tanshinone Ⅱ A sodium sulfonate injection , The control group was given only tanshinone Ⅱ A sodium sulfonate treatment, 10d for a course of treatment. Results The total effective rate in the treatment group was 96.7%, which was higher than that in the control group (84.6%), the difference was statistically significant (P <0.05). No obvious adverse reactions were observed in both groups, and the treatment was well tolerated. Conclusions Alprostadil injection combined with sodium tanshinone Ⅱ A sulfonate injection is superior to tanshinone Ⅱ A sulfonate injection in treatment of ischemic vertigo.