论文部分内容阅读
1例71岁男性患者因胃溃疡及幽门梗阻行胃次全切除术后出现肠瘘和腹腔真菌感染,给予氟康唑治疗后出现皮肤过敏反应,换用米卡芬净50 mg入0.9%氯化钠注射液100 ml,1次/d静脉滴注。输注约65 ml时,患者突然出现全身发绀、呼吸急促,排棕红色尿。实验室检查示白细胞计数52.5×109/L,红细胞计数2.7×1012/L,血红蛋白78 g/L,血小板计数118×109/L;血清尿素氮21.5 mmol/L,肌酐113μmol/L;尿隐血200 cell/μl,红细胞满视野。立即停止输液,给予血液透析等治疗,情况逐渐好转。2周后血尿常规及肾功能检查基本恢复正常。
A 71-year-old male patient with enteric fistula and peritoneal fungal infection after subtotal gastrectomy due to gastric ulcer and pyloric obstruction had an allergic skin reaction after treatment with fluconazole, with 50 mg of micafungin and 0.9% of chlorine Sodium injection 100 ml, 1 / d intravenous infusion. Infusion of about 65 ml, the patient suddenly appeared systemic cyanosis, shortness of breath, row of reddish urine. Laboratory tests showed a white blood cell count of 52.5 × 109 / L, a red blood cell count of 2.7 × 1012 / L, a hemoglobin of 78 g / L, and a platelet count of 118 × 109 / L; serum urea nitrogen of 21.5 mmol / L; creatinine of 113 μmol / L; Cell / μl, red blood cells full field of view. Immediately stop infusion, giving hemodialysis and other treatment, the situation gradually improved. After 2 weeks hematuria routine and renal function tests returned to normal.