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基因转移的特异性包括组织细胞识别的特异性和转移基因整合与表达的特异性,本文在组织细胞识别水平上就近年来基因治疗靶向性载体的发展作了综述和评价,并着重讨论了靶向性反转录病毒载体构建的主要策略。
The specificity of gene transfer includes the specificity of tissue cell recognition and the specificity of gene integration and expression. In this paper, the development of targeted gene therapy vectors in recent years is reviewed and evaluated. The main strategy for constructing retroviral vectors.