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目的 观察伴有远处转移的恶性肿瘤患者血液流变学的变化。方法 对 6 0例正常健康人、10 1例恶性肿瘤患者 ,其中 5 0例发生了远处转移 ,采用LBY N6型血液粘度计 ,测定全血粘度、血浆粘度、红细胞压积、全血还原粘度、红细胞聚集指数、纤维蛋白原。结果 恶性肿瘤患者的全血粘度、血浆粘度、全血还原粘度、纤维蛋白原高于健康对照组。伴有远处转移的恶性肿瘤患者全血粘度、红细胞聚集指数、纤维蛋白原显著高于无转移的恶性肿瘤患者。结论 恶性肿瘤患者发生血液流变学的改变 ,血液流变学的异常可能会促进肿瘤发生血道转移。
Objective To observe the changes of hemorrheology in patients with distant metastasis of malignant tumors. Methods 60 cases of normal and 101 cases of malignant tumor patients, of which 50 cases of distant metastasis occurred, the use of LBY N6 type blood viscosity meter, the determination of whole blood viscosity, plasma viscosity, hematocrit, whole blood reducing viscosity , Erythrocyte aggregation index, fibrinogen. Results The whole blood viscosity, plasma viscosity, whole blood reducing viscosity and fibrinogen in patients with malignant tumors were higher than those in healthy controls. Viscosity, erythrocyte aggregation index, and fibrinogen were significantly higher in patients with distant metastases than those without metastases. Conclusion Hemorheological changes occur in patients with malignant tumors, abnormal hemorheology may promote tumor hematogenous metastasis.