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鼾症是由于睡眠时上呼吸道间歇性萎陷引起的呼吸障碍。为了从病理生理角度阐述OSAS和鼾症对人体的危害以及寻找一种评价手术疗效的客观指标,本研究对43例患者手术治疗前后甲皱(nailfola)微循环的加全积分值进行统计学处理,结果表明有极显著的差异(p<0.01),即治疗后微循环积分值的下降有非常显著的意义。其中以流速、红细胞聚集、清晰度以及渗出积分值的降低为著,而形态的改变无显著性差异。这说明,手术治疗鼾症短期内对改善血液流态效果较著,氧代谢对微循环形态的影响则是一个慢性的过程。在对合并高血压患者与不伴高血压患者术后微循环变化的分析研究中发现,前者术后微循环改善程度较后者为著(P<0.01)。表明高血压患者微循环对氧的敏感性更大。另一方面说明鼾症对高血压患者的影响大于对非高血压患者。
Snoring is due to intermittent collapse of the upper respiratory tract caused by sleep disordered breathing. In order to elucidate the harm of OSAS and snoring on human body from the point of view of pathophysiology and to find an objective index to evaluate the curative effect of surgery, this study statistically applied the total integral of nailfola microcirculation in 43 patients before and after operation , The results showed that there is a very significant difference (p <0.01), that is, the decline of the integral value of microcirculation after treatment has a very significant significance. Which flow rate, erythrocyte aggregation, clarity and exudative integral value as a reduction, while the morphological changes were not significantly different. This shows that surgical treatment of snoring effect of short-term to improve blood flow significantly, oxygen metabolism on the microcirculation morphology is a chronic process. In patients with hypertension and without hypertension in patients with changes in the analysis of microcirculation found that the former was better than the latter to improve the degree of microcirculation (P <0.01). Show that microcirculation in patients with hypertension more sensitive to oxygen. On the other hand shows that snoring affects hypertensive patients more than non-hypertensive patients.