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目的:探讨ER、PR在乳腺癌针吸细胞涂片上的检测及其临床意义。方法:应用免疫组化技术对78例乳腺癌病人进行针吸细胞涂片性激素受体的检测,检测结果与石蜡切片检测结果相对照。结果:两种方法,ER全部阳性者为54例,PR全部阳性者为47例。针吸细胞涂片结果显示:ER、PR的阳性例数分别为58例、50例,石蜡切片结果显示:ER、PR的阳性倒数分别为57例、48例。结论:乳腺癌针吸细胞ER、PR的检测是成功的,可为术前进行预治疗的病人及失去手术机会的晚期癌病人提供内分泌治疗的依据。
Objective: To investigate the detection and clinical significance of ER and PR in the needle smear cell smears of breast cancer. METHODS: Immunohistochemical technique was used to detect the sex hormone receptors in 78 breast cancer patients. The results were compared with those of paraffin sections. Results: Of the two methods, 54 were all positive for ER and 47 were positive for PR. The result of needle smear cell smear showed that the number of positive cases of ER and PR were 58 cases and 50 cases respectively. The result of paraffin section showed that the positive counts of ER and PR were 57 cases and 48 cases respectively. Conclusion: The detection of ER and PR in the sucker cells of breast cancer is successful. It can provide the basis for endocrine therapy for pre-treatment patients and advanced cancer patients who have lost surgery.