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【目的】探讨责任制整体护理对预防产妇产后抑郁的价值。【方法】回顾性本院产科2007至2010年100例采取传统功能制护理模式进行护理干预有产后抑郁倾向孕产妇的临床资料作为对照组，收集2011年8月至2013年2月100例采用责任制整体护理模式进行干预有产后抑郁倾向孕产妇的临床资料作为观察组，采用焦虑自评表（SAS）、抑郁自评表（SDS）对患者进行问卷评分，比较两组观察对象产后出现焦虑和抑郁的情况。【结果】观察组与对照组在入院时即分娩前SAS和SDS得分差别无统计学意义（P＞0．05）；出院时即分娩后两组的 SAS和 SDS得分差别有统计学意义（P＜0．05）；观察组产后焦虑和产后抑郁的发生程度低于对照组，差异有统计学意义（P＜0．05）。【结论】责任制整体护理可以有效的降低产妇产后焦虑和抑郁症的发生率及减轻抑郁的程度，具有一定的临床意义。“,”[Obj ective]To observe the effect of the responsibility holistic nursing care on the prevention of postpartum depression in order to provide the reference for reducing the incidence of postpartum depression.[Methods]Clinical data of 100 pregnant women and parturients with postpartum depression tendency in obstetric department of our hospital from 2007 to 2019 were retrospectively collected as control group(traditional functional nursing mode).Clinical data of 100 pregnant women and parturients with postpartum depression tendency from Aug.2011 to Feb.2013 were collected as observation group(responsibility holistic nursing care).Self-rating anxi-ety scale(SAS)and self-rating depression scale(SDS)were used for the assessment of patients.The incidence of postpartum anxiety and depression in two groups was observed and compared.The data was analyzed by using SPSS13.0 analysis.[Results]There was no significant difference in prepartum SAS and SDS on admission be-tween observation group and control group(P>0.05).There was significant difference in postpartum SAS and SDS at discharging from the hospital between two groups(P <0.05).The incidence of postpartum anxiety and depression in observation group was lower than that in control group,and there was significant difference(P <0.05).[Conclusion]The responsibility holistic nursing care can effectively reduce the incidence of postpartum anx-iety and depression and alleviate the degree of depression,so it has certain clinical significance.