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早在二十世纪三十年代,已描述过合并肠道炎性疾病的结肠扩张和败血症;所谓中毒性巨结肠,在五十年代早期还未正式命名。它是肠道炎症疾病的一种急性的、暴发性的、易于致死的合并症,不论溃疡性结肠炎还是克隆氏病,约有13%的病人发生。而其中30%的病人,中毒性巨结肠可能是该病的最初表现。结肠穿扎是死亡的最主要原因。尽管许多报道提及在积极的内科治疗以后,迅速手术可以明显地减少穿孔率、提高生存率,但仍有对内科治疗持犹豫态度者,对内科治疗的确切作用仍有争论。为了进一步明确内科治疗究竟是一种疗法呢?还是仅限于术前准备,我们研究了单纯用内科治疗成功
As early as the 1930s, colon dilatation and septicemia with inflammatory bowel disease have been described; the so-called toxic megacolon was not officially named in the early 1950s. It is an acute, fulminant and lethal comorbidity of intestinal inflammatory disease, with about 13% of patients developing ulcerative colitis or Crohn’s disease. And 30% of patients, toxic megacolon may be the first manifestation of the disease. Colon puncture is the leading cause of death. Although many reports mention that prompt surgery can significantly reduce the rate of perforation and improve the survival rate after active medical treatment, there are still people who are hesitant about medical treatment. The exact role of medical treatment remains controversial. In order to further clarify whether medical treatment is a kind of therapy? Or is limited to preoperative preparation, we studied the simple medical treatment success