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目的 证实在先天性青光眼常规手术失败的儿童小梁切除术联合丝裂霉素 C(mitomycin- C,MMC)治疗是安全有效的方法。方法 9例 (9眼 )曾行常规手术失败的先天性青光眼儿童在小梁切除术中一次应用 MMC棉片 (0 .2 g· L- 1 )置于手术创面 5 min,平均随访时间 17.6 4mo± 8.41mo(0 .2 5～ 36 mo)。结果 术前平均眼压 4.0 0± 0 .6 3k Pa(3.0 7～4.93k Pa) ,术后平均眼压 1.83± 0 .10 k Pa(1.38～ 2 .0 3k Pa) ,均保持了术前的视力水平 ,成功率 88.89% (8眼 )。基本成功率 11.11% (1眼 )。常见并发症浅前房 8眼 (88.89% )。结论 小梁切除术联合 MMC治疗在常规手术失败的先天性青光眼儿童是安全有效的方法。
Objective To confirm that trabeculectomy combined with mitomycin C (MMC) is a safe and effective method in children with congenital glaucoma. Methods 9 cases (9 eyes) of children with congenital glaucoma who had failed conventional surgery were treated with MMC cotton (0.2 g · L -1) for 5 min in trabeculectomy and the average follow-up time was 17.6 4 months ± 8.41mo (0.25-236 mo). Results The average preoperative intraocular pressure was 4.0 ± 0.63kPa (3.07 ~ 4.93k Pa) and the mean postoperative intraocular pressure was 1.83 ± 0.10 kPa (1.38 ~ 2.03k Pa) Of eyesight, the success rate of 88.89% (8 eyes). The basic success rate was 11.11% (1 eye). Common complications of shallow anterior chamber in 8 eyes (88.89%). Conclusion Trabeculectomy combined with MMC is a safe and effective method for children with congenital glaucoma who have failed conventional surgery.