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皮肤癣病为常见疾患之一,向来缺乏良好的治疗剂。十一烯酸(Urdecylenic aci■)疗效的发现,造福人类堪称非浅。194■年Keen■y等氏首先发现十一烯酸之制霉菌作用,其钠盐之制霉菌作用较当时应用之丙酸钠为强。次年,氏继报告在各种细菌培养基中十一烯酸钠之杀菌制菌效力较癸酸钠为大。1947年Foley及■氏报告百分之一的十一烯酸制剂杀病原霉菌效力较一般有效脂肪酸制剂为强。1948年Russ
Skin rickets is one of the common diseases and there is a lack of good therapeutic agents. The discovery of the therapeutic effect of undecenoic acid (Urdecylenic aci ■) is of great importance for the benefit of mankind. 194 ■ Year Keen ■ y et al. first discovered the undesired effect of undecenoic acid, and its sodium salt was stronger than the sodium propionate used at that time. In the following year, the bactericidal efficacy of sodium undecylenate in various bacterial cultures was reported to be greater than that of sodium citrate. In 1947, Foley and Sans reported that a one-hundred percent of the undecylenic acid formulation was more potent than the general effective fatty acid formulation. 1948 Russ