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目的探讨影响煤矿女性职工乳腺癌发病的相关因素,为预防乳腺癌提供依据。方法采用成组设计的病例对照研究方法,对确诊的48例女性乳腺癌患者及与其相匹配的96例对照者进行流行病学调查,并应用条件Logistic回归进行因素分析。结果单因素分析显示,月经周期规律和哺乳时间半年以上是乳腺癌的保护性因素,流产次数、女性良性生殖系病史、绝经年龄49岁以上、行经期35年及以上、有绝经症状、BMI和精神创伤、压抑是影响乳腺癌发病的危险因素;多因素Logistic回归分析显示,哺乳时间半年以上是乳腺癌发生的保护因素,流产次数、女性良性生殖系病史、行经期35年及以上和精神创伤、压抑是影响乳腺癌发生的危险因素。结论煤矿女性职工乳腺癌发生的危险因素主要是流产次数、女性良性生殖系病史、行经期35年及以上和精神创伤、压抑,今后应结合危险因素落实积极有效的防治措施,定期进行乳腺检查对乳腺癌的早期预防和治疗具有重要意义。
Objective To explore the factors that affect the incidence of breast cancer among female workers in coal mines and provide the basis for preventing breast cancer. Methods A case-control study was conducted in a group design. 48 confirmed cases of breast cancer and 96 matched controls were investigated by means of epidemiological analysis and conditional Logistic regression was used to analyze the factors. Results Univariate analysis showed that menstrual cycle regularity and breastfeeding time more than six months were the protective factors of breast cancer. The frequency of miscarriage and the history of female reproductive system were benign, the age of menopause was over 49 years old, the menstrual period was 35 years and above, Multivariate logistic regression analysis showed that breastfeeding occurred more than six months after breastfeeding, and the number of abortions, the history of female genital germ line, the menstrual period of 35 years and above, and the trauma of trauma , Depression is a risk factor for breast cancer. Conclusions The risk factors of breast cancer in female workers in coal mines are mainly the number of abortions, the history of female genital system, the menstrual cycle of 35 years and over, trauma and depression, and the implementation of positive and effective prevention and treatment measures in the future. Regular breast examinations Early prevention and treatment of breast cancer is of great significance.