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目的探讨超声引导微波热消融治疗原发性肝细胞癌的临床疗效。方法超声引导微波热消融治疗的原发性肝细胞肝癌患者作为研究组,同期实施开腹手术治疗的38例患者作为对照组,对比其临床疗效和治疗时间、住院时间、医疗费用以及不良反应等。结果两组肿瘤消除率、并发症发生率、两年内复发率及生存率比较差异无统计学意义(P均>0.05)。研究组治疗时间、住院时间、医疗费用[(36.25±30.63)min、(6.74±5.66)d、(1.18±0.44)万元]明显低于对照组[(140.23±45.21)min、(18.80±7.92)d、(2.56±1.03)万元],差异有统计学意义(P均<0.01)。研究组并发症发生率10.5%,明显低于对照组的21.1%,差异有统计学意义(P<0.05)。结论超声引导微波热消融治疗原发性肝细胞肝癌可获得与手术切除相当的治疗效果和预后,但其具备微创伤、经济实惠等优势。
Objective To investigate the clinical efficacy of ultrasound guided microwave ablation in the treatment of primary hepatocellular carcinoma. Methods Thirty-eight patients with primary hepatocellular carcinoma who underwent microwave-assisted thermal ablation guided by microwave ablation were enrolled in this study. Thirty-eight patients undergoing laparotomy during the same period were enrolled in this study. The clinical efficacy, treatment time, hospitalization time, medical expenses and adverse reactions . Results There was no significant difference in tumor elimination rate, complication rate, recurrence rate within two years and survival rate between the two groups (all P> 0.05). The study group’s treatment time, hospitalization time and medical expenses were significantly lower than those in the control group [(36.25 ± 30.63) min, (6.74 ± 5.66) days, (1.18 ± 0.44) million, [(140.23 ± 45.21) min, (18.80 ± 7.92) ) d, (2.56 ± 1.03) million], the difference was statistically significant (all P <0.01). The complication rate of the study group was 10.5%, which was significantly lower than that of the control group (21.1%), the difference was statistically significant (P <0.05). Conclusion Ultrasound guided microwave thermal ablation of primary hepatocellular carcinoma can be obtained with the surgical resection of the treatment effect and prognosis, but with minimally invasive, economical and other advantages.