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目的:探讨脑梗死患者的相关危险因素。方法:分析180例脑梗死患者及对照组的一般资料,测定两组患者血糖、血尿酸和血脂浓度,其中血脂包括:血清总胆固醇(TC)、甘油三酯(TG)、脂蛋白(a)[LP(a)]、低密度脂蛋白胆固醇(LDL-C)、高密度脂蛋白胆固醇(HDL-C)、载脂蛋白A1(Apo A1)、载脂蛋白B100(Apo B100)。结果:脑梗死组与对照组比较,年龄、性别没有差异,脑梗死组体重、家族史、吸烟史、饮酒史、糖尿病史、高血压史均高于对照组(P<0.05);脑梗死组与对照组各项临床生化指标比较,脑梗死组TC、TG、LP(a)、LDL-C、Glu及UA水平明显升高(P<0.01),HDL-C、Apo A1水平明显降低(P<0.05),Apo B100水平降低但差别无统计学意义。结论:高血压、高血糖、烟酒嗜好、高尿酸和高血脂是引起脑梗死的危险因素,定期测定脑梗死患者的血压、GLU、UA及血脂有助于判断病情及预后。
Objective: To explore the related risk factors of patients with cerebral infarction. Methods: The general data of 180 patients with cerebral infarction and control group were analyzed. The levels of blood glucose, serum uric acid and blood lipid were determined in two groups of patients. The levels of serum total cholesterol (TC), triglyceride (TG), lipoprotein (a) [LP (a)], low density lipoprotein cholesterol (LDL-C), high density lipoprotein cholesterol (HDL-C), apolipoprotein A1 (Apo A1), apolipoprotein B100 (Apo B100). Results: There was no difference in age and sex between the cerebral infarction group and the control group. The body weight, family history, smoking history, drinking history, diabetes history and the history of hypertension in the cerebral infarction group were higher than those in the control group (P <0.05) Compared with the control group, the levels of TC, TG, LP (a), LDL-C, Glu and UA were significantly increased (P <0.01) and the levels of HDL-C and Apo A1 were significantly decreased <0.05), Apo B100 levels decreased but the difference was not statistically significant. Conclusion: Hypertension, hyperglycemia, alcohol and tobacco addiction, hyperuricemia and hyperlipidemia are the risk factors of cerebral infarction. Regular measurement of blood pressure, GLU, UA and lipids in patients with cerebral infarction can help to determine the condition and prognosis.