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奥美拉唑能特异性作用于胃粘膜上壁细胞表面的质子泵(即H~+,K~+-ATP酶),对各种刺激引起的胃酸分泌(包括基础胃酸分泌)都肓强而持久的抑制作用。它能加速十二指肠溃疡的愈合;治疗胃溃疡的疗效至少与雷尼替丁相似。应用其高剂量可降低溃疡病复发率。奥美拉唑治疗返流性食管炎和卓-艾综合征也有突出的疗效。本品不良反应少见,也很轻微。
Omeprazole can specifically act on the surface of the gastric mucosa cell proton pump (ie, H ~ +, K ~ + -ATP enzyme), a variety of stimuli-induced gastric acid secretion (including basal gastric acid secretion) are strong Long lasting inhibitory effect. It can accelerate the healing of duodenal ulcer; the efficacy of treating gastric ulcer is at least similar to that of ranitidine. Application of high doses can reduce the recurrence rate of ulcer disease. Omeprazole treatment of reflux esophagitis and Zhuo - Ai syndrome also have outstanding efficacy. Adverse reactions to this product is rare, but also very slight.