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目的:探讨应用华法林抗凝治疗过程中临床药师进行药学监护的模式及必要性。方法:通过几个典型病例,对华法林抗凝治疗患者的药学监护内容进行分析和讨论。结果:临床药师经对国际标准化比率的监测,发现了华法林抗凝作用的多个影响因素,因此在治疗过程中应对其进行严密的药学监护,以提高患者长期抗凝治疗的安全性。结论:临床药师应从个体化角度出发,开展用药监护及宣教工作,合理应用华法林抗凝,提高患者的用药依从性及自我监测、自我调整能力。
OBJECTIVE: To explore the mode and necessity of clinical pharmacists’ clinical care during warfarin anticoagulation therapy. Methods: Through several typical cases, the content of pharmaco-nursing of warfarin anticoagulant therapy was analyzed and discussed. Results: After monitoring the international standardization rate, clinical pharmacists found many factors influencing anticoagulant effects of warfarin. Therefore, they should be closely monitored during the course of treatment to improve the safety of long-term anticoagulation therapy. Conclusion: Clinical pharmacists should start from the individual point of view, to carry out drug custody and missionary work, rational use of warfarin anticoagulant, improve patient compliance and self-monitoring, self-adjusting ability.